Clinical Procedures

How to Use Cerasorb® Dental Successfully

1. To prepare the graft bed, bone fragments and necrotic tissue must be carefully removed before applying Cerasorb. Do this by gently perforating the tissue with a burr. Direct contact with perforated vital bone is essential for Cerasorb’s function as a bone regeneration material.
2. The Cerasorb granules should be mixed with the patient’s fresh blood from the defect region or with venous blood at about a 1/3 blood to 2/3 Cerasorb ratio (see photo at right) before application to the defect. For the convenience of the clinician, sterile one-time-use syringes are included with Cerasorb to provide easy blood draw from the surgical site and easy mixing.
3. The bone defect must be completely filled with intact granules. Strong compacting or destruction of granule structure (e.g., by crushing) must be avoided. The porous structure of the material makes it possible for the bone cells and blood vessels to grow into the granule matrix, which is resorbed even from within and simultaneously substituted by the patient’s local bone.
4. Overfilling must be avoided to allow for a tension-free closure.
5. The mucoperiosteal flaps can be sutured to achieve primary closure and to minimize particle loss. In some cases, the surgeon may place a surgical dressing or membrane such as EpiGuide over the wound.
6. Cerasorb’s radio-opaqueness allows the healing process to be monitored (see x-ray at right from Dr. Robert Horowitz, Scarsdale, NY, showing Cerasorb granules at one month).

If you have additional questions, refer to the MSDS and IFU in the Cerasorb package or refer to the Frequently Asked Questions.